Federal regulations require that all procedures involving the use of animals be approved by an Animal Care and Use Committee, prior to initiation of the project or award of extramural funding. To comply with these regulations, these forms must be completed by the person proposing the animal use. All documents must be typed or prepared legibly or they will be returned to the investigator.

The procedure for submitting and obtaining approval for the research/teaching application will be as follows:

1. Original Application Submit the completed Animal Care and Use Application to your Departmental BIACUC Representative.

2. Review by the Department/School Committee (where appropriate) Please check with your department/school for deadlines and appropriate number of copies to submit.

3. Review by the Bloomington Institutional Animal Care and Use Committee

4. Disposition (principal investigator will be notified in writing)
   • A. Approval
     
   • B. Provisional Approval (returned to the principal investigator for additional information before approval.)
     
   • C. Denial

5. Annual Review A status report must be filed with BIACUC on an annual basis (send one original). An Annual Review form will be furnished for your completion. It is important that the investigator or the investigator's departmental chairperson complete this annual form if the study is discontinued for any reason prior to receiving this form. This annual review form must be completed even if the study was never initiated or was terminated for any reason.

6. Amendments Investigations are required to report any changes related to their research study via an amendment form (send one original). The revisions or additions to the research study should be underlined or highlighted and reference made to the study number assigned by BIACUC.

7. File Maintenance It is important for the investigator to KEEP A COPY of every document related to the research study which is submitted to the Department/School or BIACUC. For audit purposes, these documents must be kept for at least three (3) years after terminating the study. The BIACUC will NOT be responsible for duplicating any information submitted.

Important: Written approval must be obtained prior to initiating the research, making amendments to the research, or ordering the animals.

Forms are available from your department committee or Norma Hollingsworth, Risks Office, Bryan Hall, 110.